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Canker sores


canker_soreDefinition

Canker sores are small sores or ulcers that appear inside the mouth. They are painful, self-healing, and can recur.

Description

Canker sores occur on the inside of the mouth, usually on the inside of the lips, cheeks, and/or soft palate. They can also occur on the tongue and in the throat. Often, several canker sores will appear at the same time and may be grouped in clusters. Canker sores appear as a whitish, round area with a red border. The sores are painful and sensitive to touch. The average canker sore is about one-quarter inch in size, although they can occasionally be larger. Canker sores are not infectious.

 

Approximately 20% of the U.S. population is affected with recurring canker sores, and more

women than men get them. Women are more likely to have canker sores during their premenstrual period.

 

Canker sores are sometimes confused with cold sores. Cold sores are caused by herpes simplex virus. This disease, also known as oral herpes or fever blisters, can occur anywhere on the body. Most commonly, herpes infection occurs on the outside of the lips and the gums, and much less frequently on the inside the mouth. Cold sores are infectious

 

Causes and symptoms

The exact cause of canker sores is uncertain, however, they seem to be related to a localized immune reaction. Other proposed causes for this disease are trauma to the affected areas from toothbrush scrapes, stress, hormones, and food allergies. Canker sores tend to appear in response to stress. The initial symptom is a tingling or mildly painful itching sensation in the area where the sore will appear. After one to several days, a small red swelling appears. The sore is round, and is a whitish color with a grayish colored center. Usually, there is a red ring of inflammation surrounding the sore. The main symptom is pain. Canker sores can be very painful, especially if they are touched repeatedly, e.g., by the tongue. They last for one to two weeks.

 

Diagnosis

Canker sores are diagnosed by observation of the blister. A distinction between canker sores and cold sores must be made because cold sores are infectious and the herpes infection can be transmitted to other people. The two sores can usually be distinguished visually and there are specific diagnostic tests for herpes infection.

 

Treatment

Since canker sores heal by themselves, treatment is not usually necessary. Pain relief remedies, such as topical anesthetics, may be used to reduce the pain of the sores. The use of orticosteroid ointments sometimes speeds healing. Avoidance of spicy or acidic foods can help reduce the pain associated with canker sores.

 

Alternative treatment

Alternative therapies for canker sores are aimed at healing existing sores and preventing their recurrence. Several herbal remedies, including calendula (Calendula officinalis), myrrh (Commiphora molmol ), and goldenseal (Hydrastis canadensis), may be helpful in the treatment

of existing sores. Compresses soaked in teas made from these herbs are applied directly to the sores. The tannic acid in a tea bag can also help dry up the sores when the wet tea bag is used as a compress. Taking dandelion (Taraxacum officinale) tea or capsules may help heal sores and also prevent future outbreaks. Since canker sores are often brought on by stress, such stressrelieving techniques as meditation, guided imagery, and certain acupressure exercises may help prevent canker sores or lessen their severity.

 

Prognosis

Canker Sore Treatment

 

Self-Care at Home

    * Try rinsing your mouth with a solution of ½ teaspoon salt dissolved in 8 ounces of water.

    * Another mixture that may be helpful consists of 1-2 tablespoons of Maalox mixed with ½ tablespoon of liquid diphenhydramine (Benadryl). Swish a teaspoonful in your mouth and spit it out. This can be done four times a day.

    * A number of medications are available over the counter, for example, calamine (Calamox) lotion.

    * Liquids or ointments with a numbing ingredient such as benzocaine (Anbesol, Oragel, Orabase, Zilactin-B, Tanac) help relieve the discomfort of canker sores.

 

 Medical Treatment

 Although there is no cure for canker sores, treatment can decrease symptoms, reduce the likelihood that they will return, and prolong periods of remission.

    * Applying certain steroid salves directly to the sore is effective if you use the salve early in an attack. If over-the-counter medications do not help, a common prescription consists of triamcinolone acetonide, a corticosteroid, in a sticking dental paste (Kenalog in Orabase). Typically, you apply the paste to the lesions three times daily. More recently, doctors have prescribed amlexanox (Aphthasol). Although no one knows why amlexanox works, it may be related to its anti-inflammatory and anti-allergic effects.

   * Tetracycline suspensions (Achromycin, Nor-tet, Panmycin, Sumycin, Tetracap) used as a mouthwash can relieve pain and accelerate healing.

     * The doctor can prescribe viscous lidocaine (an anesthetic) to numb the ulcers before meals and at bedtime, making it easier for you to eat.

     * A slurry made with Carafate, a prescription medication used to treat peptic ulcers, has been reported to successfully coat canker sores, promoting comfort and healing. However, the FDA has not approved the use of Carafate officially for canker sores.

     * The doctor may prescribe folic acid, iron, or vitamin B12 supplements if you are deficient in these. In such cases, you may require several months of therapy to improve. No benefit has been shown, however, from taking these vitamins if you are not deficient.

     * For unknown reasons, some women may develop new attacks or worsening of canker sores during their premenstrual phase. An estrogen-dominant oral contraceptive may help if given for four to six months.

     * In extremely severe cases, doctors may consider giving oral doses of corticosteroids, if they believe the benefits of treatment exceed the risks of oral steroids. Risks of steroid therapy include weight gain, weakening of the immune system, brittle bones, increase in gastric acidity leading to ulcers, and others.

     * Cimetidine (Tagamet) may be useful in treating canker sores. This is the same medication that decreases acid production by the stomach and is used for peptic ulcers and heartburn. The FDA has not approved cimetidine officially for the treatment of canker sores.

     * Surprisingly, some recent studies have found thalidomide effective for managing severe cases of canker sores. Thalidomide is available only experimentally, having been taken off the market years ago because it caused severe birth defects. The drug also can be toxic to the nerves. Hence, use of thalidomide is restricted to research studies.

     * Additional drugs reported to be beneficial include colchicine, pentoxifylline (Trental), and dapsone (Avlosulfon). Colchicine may aid prevention as well as treatment. Interferon and levamisole also may be useful in severe cases. At this time, the FDA has approved none of these drugs for the treatment of canker sores.

     * More recently, a prescription drug, Debacterol, was released that is applied to the ulcer and helps to seal it and allow it to heal.

 

Resources

BOOKS

Larsen, D. E., editor. Mayo Clinic Family Health Book.

New York: William Morrow, 1996.

John T. Lohr, PhD

The eMedicineHealth

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